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With all the controversy surrounding stem cells you may have missed hearing
about many of the benefits for the health and medical fields. You may not even
be aware that stem cells already have many applications for treating disease.
Their potential to treat even more diseases in the future means that scientists
are working hard to learn about how stem cells function and how they can treat
some of the more serious diseases affecting the world.
Stem Cells and Human Development
Stem cells have enormous potential in health and
medical research but to fully harness this potential, scientists are studying
how stem cells transform, or differentiate, into the diverse range of
specialised cells that make humans what they are today. Because diseases such
as cancer or conditions such as birth defects are thought to occur because of
problems in the differentiation process, an understanding of the development
that happens in normal cells will help scientists treat the developmental
errors that can occur.
Stem Cells and Cell-Based Therapies
Another potential application of stem cells is to form
cells and tissues for medical therapies. Currently, it is donated organs and
tissues that are substituted for damaged or dysfunctional ones. Sadly, the
number of people awaiting a transplant is much higher than the number of
available organs. Transplant waiting lists are enormous and many people die
awaiting transplants. Stem cells offer a viable source of replacement cells to
treat diseases and can potentially reduce the morbidity and mortality for those
awaiting transplants. Some of the areas that stem cells can benefit include:
- Parkinson's
disease
- Type I
diabetes
- Arthritis
- Burn
victims
- Cardiovascular
diseases
Potential to Reverse Diseases
By directing stem cells to differentiate into specialised
cell types, there is the exciting possibility to provide a renewable source of
replacement cells for those suffering from diseases.
The potential to reverse diseases is also not a foreign one.
Heart Attack - For example, a patient who has suffered from a heart attack
and sustained heart damage could have the damaged tissue replaced by healthy
new muscle cells.
Parkinson's Disease - The destruction of brain cells in conditions such as
Parkinson's disease can hopefully be reversed with the replacement of new,
healthy and functioning brain cells.
Genetic Defects - Even more promising is the potential to address genetic
defects that are present from birth by restoring function and health with the
introduction of normal healthy cells that do not have these defects.
Burn
Victims
Burn victims tend to endure an enormous amount of pain from
their wounds as well as frustration from the challenges of healing. Instead of
donor tissues being donated, stem cells could be used to produce new and
healthy tissues. This is essentially similar to therapies already being used,
such as bone marrow transplants, where stem cells create different specialised
blood cells.
Scientists aim to locate and remove specific stem cells from a tissue
and then trigger them to differentiate outside of the body before transplanting
them back into the patient to replace damaged tissues. In burn victims, a very
small piece of the skin can be progressively grown, allowing doctors to cover a
burn that is often much larger than the original size of the skin piece.
Stem
Cells and Drug Testing
Stem cells have an important benefit for the pharmaceutical
field. New drugs can be tested on stem cells to assess their safety before
testing drugs on animal and human models. For example, a cancer cell line could
be created to test an anti-tumour drug. If the conditions can be perfectly
replicated, testing drugs could provide very accurate results.
The current benefits of stem cell usage are already well
documented and it is expected that continued research will pave the way for new
treatments. For those suffering from serious diseases, stem cells offer hope
for effective treatment or perhaps even a reversal of the disease. Time will
confirm the full success of stem cell therapies and continued research should
teach us more about using stem cells to treat debilitating medical conditions.
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